Ryan pitched in 29 games for Greenville in 1966, going 17-2 with a 2.51 ERA and 272 strikeouts in 183 innings.
In 87 innings, Scott struck out 112 and compiled a 6-3 record with 4 saves and a 2.06 ERA.
With Rye playing outfield for the Twins, Winston-Salem would win the Piedmont League pennant in 1928 and defeat the High Point Pointers 4 games to 3 in the playoffs to claim the Piedmont League Championship.
Hoyt went 15-3 his rookie year, leading the NL in games (71), winning percentage (.833) and ERA (2.43).
North Carolina brothers Rick and Wes Ferrell set a MLB record in 1933.
Bob Allison and Harmon Killebrew set a Major League Record in 1963.